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KMID : 0377619770330010041
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Korean Jungang Medical Journal
1977 Volume.33 No. 1 p.41 ~ p.46
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Clinical Relationship between Craniocerebral injuries and Posttraumatic Epilepsy
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Abstract
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The relationship between head injury and epilepsy has long been debated and studied. In the, clinical and basic investigations of this problem, however, one aspect has often been discussed but scientifically neglected; little has been reported concerning the evaluation of pharmacologic prophylaxis in this disorder.
Head injury is now one of the commonest causes of fits which may develop soon after. the injury or month later. The risk of epilepsy are related to. whether the dura is penetrated or not.
Early epilepsy is the term used for convulsion at the time of injury or when the patient is still suffering from the direct effects of trauma. In practice, the majority of early epilepsy occurs within the first week following trauma. Late epilepsy is used to describe convulsive seizures attributed to the late. effects of injury after the acute symptoms and signs have disappeared.
In a series of 381 cases of emergency craniotomy for head injury, 19 per cent developed epilepsy, the incidence of early seizures being 8 per cent and of late: seizures, 11 per cent.
In the study of 226 cases of EEG following craniocerebral injury reviewed, 29 per cent showed abnormalities features, the relatively high incidence of a normal record in unselected head injury.
Convincing statistical evidence concerning the effect of the prophylactic administration of drugs has not been discovered but many investigators have. often been mentioned that there are possibility of preventing posttraumatic epilepsy in the early study of pharmacologic prophylaxis of posttraumatic epilepsy.
Judging from experience with epilepsy after head injury, it seems wise to persist With prophylactic anti convulsants for, at least 6 months to two or three years.
The traumatic epilepsy would appear unwise to look to the EEG for guidance about the epilepsy developing or the wisdom of stopping treatment common sense and clinical judgment are more reliable.
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